Buy and get information for Potassium iodide, A.R., GRM1086, 7681-11-0, Chemicals, Inorganic, AR Grade In 2017, the Dutch government distributed pills to hundreds of thousands of residents who lived within a certain distance of nuclear power plants and met some other criteria. Dawn Scientific Inc is women owned small business located in central New Jersey. As reported by the NRC, studies after the accident showed that "As of 1996, except for thyroid cancer, there has been no confirmed increase in the rates of other cancers, including leukemia, among the... public, that have been attributed to releases from the accident. Uses for organic iodine derivative compounds include food supplementation, disinfectants and pharmaceutical use. In the event of a radioiodine release the ingestion of prophylaxis potassium iodide, if available, or even iodate, would rightly take precedence over perchlorate administration, and would be the first line of defence in protecting the population from a radioiodine release. Thus, a drop of SSKI provides 50/0.15 = 333 times the daily iodine requirement, and a standard KI tablet provides twice this much. Elsievier Publishing, US Food and Drug Administration, FDA Talk Paper: Guidance on Protection Against Thyroid Cancer in Case of a Nuclear Accident, US Nuclear Regulatory Commission, Assessment of the Use of Potassium Iodide (KI) As a Public Protective Action During Severe Reactor Accidents Quoting Thyroid Cancer in Children of Belarus Following the Chernobyl Accident, NUREG-1633, United Nations: Office for the Coordination of Humanitarian Affairs (OCHA), Chernobyl, a Continuing Catastrophe, New York and Geneva, 2000, World Health Organization's List of Essential Medicines, https://www.fda.gov/regulatory-information/search-fda-guidance-documents/potassium-iodide-thyroid-blocking-agent-radiation-emergencies, "43-2035 AdreView Panel PI 091908:Layout 1", https://web.archive.org/web/20111007202042/https://www.eanm.org/scientific_info/guidelines/gl_radio_ther_benzyl.pdf?PHPSESSID=46d05b62d235c36a12166bf939b656c7, "Guidelines for Iodine Prophylaxis following Nuclear Accidents", "Potassium Iodide as a Thyroid Blocking Agent in Radiation Emergencies", https://www.cdc.gov/nceh/radiation/emergencies/ki.htm, "POTASSIUM IODIDE - ORAL (SSKI) side effects, medical uses, and drug interactions", "Iodide as a Fluorescence Quencher and Promoter—Mechanisms and Possible Implications", Ullmann's Encyclopedia of Industrial Chemistry, "Iodide prophylaxis in Poland after the chernobyl reactor accident: Benefits and risks", "Vegetables near stricken plant test high for radiation", six questions about a half of million iodine pills, "REQUEST FOR INFORMATION:CRITICAL FOREIGN DEPENDENCIES", "Potassium Iodide Dosage Guidelines & Frequently Asked Questions", "Potassium Iodide: An Antidote for Radiation Exposure", "Oral potassium iodide for the treatment of sporotrichosis", "Successful therapy of refractory erythema nodosum associated with Crohn's disease using potassium iodide", World Health Organization's guidelines for iodine prophylaxis following a nuclear accident, Airborne radioactive particulate monitoring, https://en.wikipedia.org/w/index.php?title=Potassium_iodide&oldid=998383668, World Health Organization essential medicines, Wikipedia articles needing page number citations from May 2012, Articles with dead external links from July 2020, Chemical articles with unknown parameter in Infobox drug, Articles containing unverified chemical infoboxes, Articles with unsourced statements from April 2013, Articles with unsourced statements from August 2020, Articles with unsourced statements from October 2011, Wikipedia medicine articles ready to translate, Creative Commons Attribution-ShareAlike License, iOSAT, SSKI, ThyroSafe, ThyroShield, others, Saturated solutions of potassium iodide can be an emergency treatment for, Iodide solutions made from a few drops of SSKI added to drinks have also been used as, Potassium iodide has been used for symptomatic treatment of. In this report, effects of protein iodination on elicitogenic activity in guinea pig iodine allergy model and iodinated protein antigen … [citation needed] By saturating the body with a source of stable iodide prior to exposure, inhaled or ingested 131I tends to be excreted, which prevents radioiodine uptake by the thyroid. Potassium Iodide is precisely formulated by using the finest quality chemical compounds and advanced technology by deft professionals at vendor's end. Comparison Of Organic And Inorganic Compounds A.1 Physical Properties Name 1. When a person takes KI, the stable iodine in the medicine gets absorbed by the thyroid. Centers for decease control and prevention |, McCance; Huether. It is colourless to white, it appears as cubical crystals, or powder or white granules. 500g. US Nuclear Regulatory Commission, Report on the Accident at the Chernobyl Nuclear Power Station, NUREG-1250. 90 ($0.13/Count) Potassium iodide is a component in the electrolyte of dye sensitised solar cells (DSSC) along with iodine. A typical tablet weighs 160 mg, with 130 mg of potassium iodide and 30 mg of excipients, such as binding agents. Washington DC: American Pharmacists Association; 2004. Potassium iodide is an inorganic chemical compound which is denoted by the chemical formula KI. [9] It is on the World Health Organization's List of Essential Medicines, the safest and most effective medicines needed in a health system. Potassium iodide's (KI) value as a radiation protective (thyroid blocking) agent was demonstrated following the Chernobyl nuclear reactor disaster in April, 1986, a saturated solution of potassium iodide (SSKI) was administered to 10.5 million children and 7 million adults in Poland[25][38] as a preventative measure against accumulation of radioactive 131I in the thyroid gland. Potassium Iodide and Starch TS Category: Pharmacopoeia > US Pharmacopoeia > Test Solutions (TS) USP Ref Num: USP295 Full Name: Potassium Iodide and Starch TS Shelf Life on Ship Date: 12 Months - Store under normal laboratory conditions, at temperatures between 15°C to 25°C Vol. [4], Common side effects include vomiting, diarrhea, abdominal pain, rash, and swelling of the salivary glands. If potassium iodide upsets your stomach, take it after meals or with food or milk, unless your doctor has suggested otherwise. Shop a large selection of products and learn more about Potassium Iodide, Extra Pure, SLR, Fisher Chemical™: Other Inorganic Compounds Chemicals . Chronic overexposure can have adverse effects on the thyroid. No, you may pick up a little color from the inside due to some impurities but it is the iodine that affects the color of starch indicstor. [4] Other side effects include allergic reactions, headache, goitre, and depression. In treating over 3,000 patients, I have found three patients with "allergy" to non-radioactive inorganic iodine/iodide. It is used in table salt as the most common additive. Required fields are marked *. Shop a large selection of products and learn more about Potassium iodide, 99+%, for analysis, ACROS Organics™: Other Inorganic Compounds Chemicals . The thyroid gland is the most sensitive component of the body to radioactive iodine. Shop a large selection of products and learn more about Potassium Iodide, Extra Pure, SLR, Fisher Chemical™: Other Inorganic Compounds Chemicals . As formed under acidic conditions, hydriodic acid (HI) is a stronger reducing agent.[33][34][35]. In a small study on human subjects, who for each of their 90-day trial, ingested four 20 milligram tetraglycine hydroperiodide (TGHP) water tablets, with each tablet releasing 8 milligrams (ppm) of free titratable iodine;[29] it was found that the biological uptake of radioactive iodine in these human subjects dropped to, and remained at, a value of less than 2% the radioiodine uptake rate of that observed in control subjects who went fully exposed to radioiodine without treatment.[30]. True iodine allergy to inorganic, non-radioactive iodine is very rare. Bedford, MA: CIS-US, Inc. July 1999. Potassium iodide is an ionic compound which is made of the following ions: K I . "[40], Chernobyl also demonstrated that the need to protect the thyroid from radiation was greater than expected. Potassium iodide is an inorganic chemical compound which is denoted by the chemical formula KI. "[20], The U.S. Department of Health and Human Services restated these two years later as "The downward KI (potassium iodide) dose adjustment by age group, based on body size considerations, adheres to the principle of minimum effective dose. "[17], With the passage of time, people living in irradiated areas where KI was not available have developed thyroid cancer at epidemic levels, which is why the US Food and Drug Administration (FDA) reported "The data clearly demonstrate the risks of thyroid radiation... KI can be used [to] provide safe and effective protection against thyroid cancer caused by irradiation. [45], In the Netherlands, the central storage of iodine-pills is located in Zoetermeer, near The Hague. Naming of inorganic binary compounds - Rules for naming inorganic ionic and covalent types of chemical compounds Organic nitrogen compounds - physical data - Boiling and melting points of amines, diamines, pyrroles, pyridines, piperidines and quinolines shown together with their molecular structures, as well as molweights and density. : 100 ml For protection of the thyroid against radioiodine (iodine-131) contamination, the convenient standard 130 mg KI pill is used, if available. Because KI contains so much stable iodine, the thyroid gland becomes “full” and cannot absorb any more iodine—either stable or radioactive—for the next 24 hours. It may also be mixed into much larger volumes of juices. Melting point:681 °C (1,258 °F) Boiling point:1,330 °C (2,430 °F) It is used in the treatment of hyperthyroidism. Your email address will not be published. Potassium iodide can be conveniently prepared as a saturated solution, abbreviated SSKI. Aryl iodides are in turn used to attach aryl groups to other organics by nucleophilic substitution, with iodide ion as the leaving group. All of these doses should be compared with the far lower dose of iodine needed in normal nutrition, which is only 150 μg per day (150 micrograms, not milligrams). Melting 4. Potassium iodide, 99%, extra pure, briquettes, ACROS Organics 100g; Glass bottle Chemicals:Other Inorganic Compounds:Inorganic Iodine Compounds Formula 2. Micro Ingredients US Origin Potassium Chloride Powder, 1 Kg (2.2 Pounds), Pure Potassium Chloride Supplement, Helps Lower Blood Pressure, Non-GMO and Vegan Friendly 4.6 out of … By March 20, the US Navy instructed personnel coming within 100 miles of the reactor to take the pills. [citation needed], KI is used with silver nitrate to make silver iodide (AgI), an important chemical in film photography. It crystallises in the sodium chloride structure. A single dose of KI (potassium iodide) protects the thyroid gland for 24 hours. [36][37] For example: KI, acting as a source of iodide, may also act as a nucleophilic catalyst for the alkylation of alkyl chlorides, bromides, or mesylates. Aqueous KI3, "Lugol's solution", is used as a disinfectant and as an etchant for gold surfaces. 13 14 Composition of the Substance: 15 16 Potassium iodide is an inorganic compound +with formula KI, a salt of stable iodine. In 2012, Fleming Co. sold all its product rights and manufacturing facility to other companies and no longer exists. [3], Potassium iodide is used as a nutritional supplement in animal feeds and also in the human diet. A one-time dose at recommended levels is usually all that is needed to protect the thyroid gland. Potassium iodide is a chemical compound, medication, and dietary supplement. Potassium iodide is highly soluble in water so SSKI is a concentrated source of KI. KI (potassium iodide) blocks radioactive iodine from entering the thyroid. In all these cases however, despite the risks, the prophylaxis benefits of intervention with iodide, iodate or perchlorate outweigh the serious cancer risk from radioiodine bioaccumulation in regions where radioiodine has sufficiently contaminated the environment. Filtered product was dried in vacuum oven at 80 °C for 6 h. 2.4. [24], The World Health Organization does not recommend KI prophylaxis for adults over 40 years, unless the radiation dose from inhaled radioiodine is expected to threaten thyroid function, because the KI side effects increase with age and may exceed the KI protective effects; "...unless doses to the thyroid from inhalation rise to levels threatening thyroid function, that is of the order of about 5 Gy. Potassium iodide is a component in the electrolyte of dye sensitised solar cells (DSSC) along with iodine. Formula 2. Offered range is well tested by quality experts in order to dispatch a perfect and defect free range to patrons. [46][47], As of 2020, potassium iodide tablets are made available free of charge for all residents in all pharmacies throughout the country. Potassium iodide is a very strong reducing agent. Potassium iodide is a possible teratogen. Packaged in an amber glass bottle. Molar mass:166.0028g/mol. Tablets of potassium iodide are supplied for emergency purposes related to blockade of radioiodine uptake, a common form of radiation poisoning due to environmental contamination by the short-lived fission product 131I. [9] Some of the earliest uses included for syphilis.[9]. Iobenguane Sulfate I 131 Injection Diagnostic package insert. Organic Or State Point Bonds Inorganic? However, for several fluorophores addition of KI in μM-mM concentrations results in increase of fluorescence intensity, and iodide acts as fluorescence enhancer.[31]. [22] A likely lethal dose of salt (more than a kilogram[23]) would be needed to equal the potassium iodide in one tablet. It has a highly bitter, saline taste. Our company has a titration procedure for prevalent chrome that uses potassium iodide (KI). Potassium iodide (KI), commonly known as Potassium iodine.An inorganic compound used in the preparation of organic iodide and as a chemical reagent. Within ten years of the accident, it became clear that thyroid damage caused by released radioactive iodine was virtually the only adverse health effect that could be measured. Comparison Of Organic And Inorganic Compounds A.1 Physical Properties Name 1. Aged and impure samples are yellow because of the slow oxidation of the salt to potassium carbonate and elemental iodine.[32]. U.S. Food and Drug Administration-approved dosing of potassium iodide for this purpose with iobenguane, is as follows (per 24 hours): infants less than 1 month old, 16 mg; children 1 month to 3 years, 32 mg; children 3 years to 18 years, 65 mg; adults 130 mg.[14] However, some sources recommend alternative dosing regimens. [51] Potassium iodide may also be administered pharmaceutically for thyroid storm. Type Of 5. To guarantee a clean and stable product, our matrix is prepared using double-deionized, ASTM Type I Water. [7] [8], Potassium iodide has been used medically since at least 1820. It reacts readily with any oxidizer, including oxidizing acids such as sulfuric and nitric. The use of KI...was credited with permissible iodine content in 97% of the evacuees tested. Taking a stronger dose of KI (potassium iodide), or taking KI more often than recommended, does not offer more protection and can cause severe illness or death. Dedicated nutritional iodide tablets containing 0.15 mg (150 micrograms (μg)) of iodide, from KI or from various other sources (such as kelp extract) are marketed as supplements, but they are not to be confused with the much higher pharmaceutical dose preparations. Physical 3. At 20 degrees Celsius the solubility of KI is 140-148 grams per 100 grams of water. ESV Potassium Iodide Solution is a highly soluble form of inorganic iodide which makes it great for maintaining dissolved iodide levels in your saltwater tank. Your email address will not be published. Organic Or State Point Bonds Inorganic? The alkali metal iodide salt, over time and exposure to excess oxygen and carbon dioxide, slowly oxidizes to metal carbonate and elemental iodine, which then evaporates. Such radiation doses will not occur far away from an accident site. Kowalsky RJ, Falen, SW. Radiopharmaceuticals in Nuclear Pharmacy and Nuclear Medicine. It can help in shrinking the size of the thyroid gland and also decreases the number of thyroid hormones produced. KI is a component in some disinfectants and hair treatment chemicals. This page was last edited on 5 January 2021, at 03:49. It is produced industrially by treating KOH with iodine. For reasons noted above, therapeutic drops of SSKI, or 130 mg tablets of KI as used for nuclear fission accidents, are not used as nutritional supplements, since an SSKI drop or nuclear-emergency tablet provides 300 to 700 times more iodine than the daily adult nutritional requirement. Potassium iodide is an ionic compound which is made of the following ions: K+I−. Neonates ideally should receive the lowest dose (16 mg) of KI. This is 100% weight/volume (note units of mass concentration) of KI (one gram KI per mL solution), which is possible because SSKI is significantly more dense than pure water—about 1.67 g/mL. Since the iodide ion is a mild reducing agent, I− is easily oxidised to I2 by powerful oxidising agents such as chlorine: This reaction is employed in the isolation of iodine from natural sources. 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